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NanoZoomer® S60v2 Digital slide scanner
C16600-01
This model supports both brightfield and fluorescent imaging. It is designed for use with mega slides, allowing for the virtualization of larger tissue samples. This facilitates the digitalization of pathological tissue observation, enhancing research and drug discovery applications.
NanoZoomer is a registered trademark of Hamamatsu Photonics K.K. (EU, Japan, UK, USA).
Special functions for fluorescence scanning
In addition to our proprietary high-sensitivity camera, we have adopted an epi-illumination optical system with a filter-switching mechanism, enabling multi-fluorescent scanning across up to 6 channels. Image files are output for each channel, allowing for single-wavelength viewing or overlaying multiple wavelengths for comprehensive analysis.
Example: Multi-stained mouse fluorescent specimen (6 channels) “Image 1”
● Scanning Speed (20× Mode): Approx. 16 minutes
● Scan Area: 7 mm × 12 mm
● Fluorescent Dyes: DAPI / Aqua / Green / Gold / Red / Far Red
● Exposure Times: 80 ms / 32 ms / 112 ms / 224 ms / 224 ms / 112 ms
● Scaling: 8× each
Image 1
Functions
Scaling Function
By applying scaling processing to the fluorescence intensity values during scanning, bright fluorescent images can be obtained with shorter exposure times. The exposure time can be reduced to as short as 1/8 of the original time, resulting in faster scans and reduced risk of fluorescence fading.
Scan Area (40× mode): 10 mm × 10 mm
Fluorescence Filters: For DAPI / FITC / TRITC
* Scan time is based on actual measurements and includes the entire process from slide loading to scan completion.
Image 2
Example: Mouse kidney fluorescent specimen “Image2”
● Scanning Speed (40× Mode): Approx. 9 minutes
● Scan Area: 7 mm × 13 mm (The image is a partial field of view)
● Fluorescent Dyes: DAPI / Alexa 488 / Alexa 568
● Exposure Times: 10 ms / 5 ms / 5 ms
Focus Offset Function
As seen in Image 3, the focus offset function enables precise adjustment of the focus plane for each wavelength. By setting the focus offset value for each stained object, clear images with accurate focus can be obtained across all wavelengths.
Image 3
Multi-slide Scanning Capacity
- Up to 60 standard slides
- Up to 30 mega slides
High-speed Scanning* (Brightfield)
- 20× mode: 60 s/slide
- 40× mode: 75 s/slide
*Scanning times are based on a 15 mm × 15 mm area with 5 focus points.
Specifications
| Product name | NanoZoomerⓇ S60v2 Digital slide scanner | |
|---|---|---|
| Product number | C16600-01 | |
| Scanning speed *1 | 20× mode | Approx. 60 s (15 mm x 15 mm) |
| 40× mode | Approx. 75 s (15 mm x 15 mm) | |
| Objective lens | 20× NA 0.75 (User can select 20× or 40× mode at start of scanning) | |
| Compatible glass slides *2 | Standard slide | 25.0 mm to 26.0 mm × 75.0 mm to 76.0 mm (Thickness 0.9 mm to 1.2 mm) |
| Mega slide (option) | 51.0 mm to 52.0 mm × 75.0 mm to 76.0 mm (Thickness 0.9 mm to 1.2 mm) | |
| Slide loader | Standard slide | Up to 60 slides (20 slides × 3 cassettes) *3 |
| Mega slide | Up to 30 slides (10 slides × 3 cassettes) *3 | |
| Scanning resolution | 20× mode | Approx. 0.46 μm/pixel |
| 40× mode | Approx. 0.23 μm/pixel | |
| Focusing method | Pre-Focus map | |
| Z-stack feature | Included (Up to 99 layers, spacing 0.1 μm or more) | |
| Image compression | Compressed Images (JPEG), Uncompressed Images (8 bit) | |
| Readable barcodes | 1D Barcodes | Code 39, Code 128, Interleaved 2 of 5, Codabar, EAN-8 and UPC-E |
| 2D Barcodes *4 | DataMatrix (ECC200), QR CodeⓇ (QR Code Model-1, QR Code Model-2) | |
| Power supply | AC 100 V to AC 240 V | |
| Power consumption (Scanner only) | Approx. 120 VA | |
*1 When it scans an area of 15 mm × 15 mm square with 5 focus points.
*2 Standard slide is a single slide, mega slide is a double-width, large slide.
*3 Up to 3 cassettes can be set with combination of standard and mega-sized slides.
*4 Optional software is required to read 2D barcodes.
Dimensions
Important Notice
Important Notice
In the USA, the C13220-01MD NanoZoomer S360MD Slide scanner system can be used for primary diagnosis in the following validated FDA-cleared displays:
・JVC JD-C240BN01A *The display is FDA cleared for use with the NanoZoomer S360MD.
・BARCO MDPC-8127 *The display itself is FDA cleared.
In Europe, the following products are regulatory compliant for IVDR (EU), UK MDR2002 (UK) and IvDO (CH) for in vitro diagnostic use:
C13220-21MDEU NanoZoomer S360MD Slide scanner system, C16600-21MDEU NanoZoomer S60v2MD Slide scanner system, C16300-21MDEU NanoZoomer S20MD Slide scanner system and C17400-21MDEU NanoZoomer S540MD Slide scanner system.
In China, the following products are registered for in vitro diagnostic use:
C13220-01 NanoZoomer S360, C13239-01 NanoZoomer S210, C13210-01 NanoZoomer S60 and C13140-01 NanoZoomer-SQ.
In Canada, C13220-31 NanoZoomer S360 and C16300-31MDCA NanoZoomer S20MD Slide scanner system have Medical Device License.
In Taiwan, C13220-01 NanoZoomer S360 is registered as medical device.
In Korea, C13220-61MDK NanoZoomer S360MD Slide scanner system and C16300-61MDK NanoZoomer S20MD Slide scanner system are registered as in vitro diagnostic medical device.
In Japan, C13220-11MDJ NanoZoomer S360MD Slide scanner system and C16300-11MDJ NanoZoomer S20MD Slide scanner system are approved as medical devices.
In Türkiye, C13220-21MDEU NanoZoomer S360MD Slide scanner system, C16600-21MDEU NanoZoomer S60v2MD Slide scanner system and C16300-21MDEU NanoZoomer S20MD Slide scanner system are registered as medical devices.
In Israel, C13220-21MDEU NanoZoomer S360MD Slide scanner system and C16600-21MDEU NanoZoomer S60v2MD Slide scanner system are registered as medical devices.
For other countries, the NanoZoomer series are for research use only and not permitted to use for clinical diagnostic purpose.
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